- Name: Apcalis SX
- Brand Name: Apcalis SX
- Active ingredient: Tadalafil
- Used for: Erectile Dysfunction (Impotence) treatment
- Dosages (mg): 20
- Drug Class: Phosphodiesterase type 5 (PDE5)
- What is Apcalis SX
- How does Apcalis SX Work?
- Interesting Facts
- Off-label Uses of Apcalis SX
- Drug Interactions
- Warnings, Precautions & Contraindications
- Customer Questions About Apcalis SX
- Customer Reviews
What is Apcalis SX (Tadalafil)
Apcalis SX is issued in the form of jelly. It represents a remedy for men suffering from erectile dysfunction. Erectile dysfunction shows itself in incapacity to achieve erection and keep penis in erected state important for successful sexual intercourse. Apcalis SX’s quality, efficiency, dosage and other aspects are identical to Cialis. It is generally accepted that tadalafil in the form of jelly takes a faster action and gives less side-effects than traditional tableted form due to its quick absorption rate. Apcalis SX starts its effect in 10-15 minutes and lasts 36-48 hours. Besides, jelly is easier to swallow which is quite convenient for aged patients or persons with disturbed deglutitory function.
Apcalis SX costs less than its original, Cialis. Its active substance, Tadalafil falls into the group of PDE5 inhibitors. Sexual stimulation causes relaxation of penis vessels and makes its filling with blood easier. As a result, erectile function improves. It should be mentioned that Apcalis SX doesn’t work without sexual stimulation. You need to start foreplay like if you haven’t taken any medicine before. You have to find the reason of your dysfunction before you start taking Apcalis SX and its analogues.
Apcalis SX is taken for treatment of erectile dysfunction. It is prescribed when a man has difficulties in achieving erection and its keeping for enough time significant for sexual intercourse.
A patient should open a bag and either press out the contents right into mouth or on spoon. It is important to let the medication get absorbed in mouth before swallowing its remnants. Medicine’s action will last 24-36 hours, so you will have enough time to have sex as much as you want. Recommended dose of medication makes 20mg of tadalafil. Apcalis SX in the form of jelly is taken before expected sexual activity regardless the food acceptance. Maximal daily dosage is once per day.
The main advantages of Apcalis SX are the following:
- The onset time is very fast and effect is long-lasting. Drug’s effect may be observed in 10 minutes after the intake lasting not less than 36 hours.
- The jelly is very convenient to take. It doesn’t require water or spoon.
- Package includes from 5 to 20 bags of jelly with various flavors, such as orange, cherry, mango, mint, grapes, chocolate. Therefore, it will catch fancy of everyone.
- This effective and safe remedy among analogous generics has a small number of side-effects and counter-indications. The remedy should be taken with care by men with cardiac diseases and leukemia. It is not to be taken by women and persons under 18 years of age as well as along with nitrogen oxide donors. Side-effects are observed very seldom and may be shown in form of vertigo, nausea, headache, blushing.
- Apcalis SX is very effective for treatment of erectile dysfunction which improves psychic condition of a man, boosts self-confidence, prevents from apprehension and depressive condition.
- Jelly is easy and convenient to keep. It doesn’t require special storage conditions.
How does Apcalis SX Work?
Tadalafil’s mechanism of action is based on PDE5 inhibition. Sexual arousal in cavernous bodies causes local release of nitrogen oxide. While connecting with guanylate cyclase, nitrogen oxide forms cyclic guanosine monophosphate (cGMP). This composition is responsible for relaxation of unstriated muscles. While penis muscles are strained, blood cannot get in cavernous bodies completely. In case of erectile dysfunction, in the described process cyclic guanosine monophosphate is disturbed by PDE5 inhibitor.
What is tadalafil used for? Via stomach the active substance gets in blood operatively. It blocks PDE5 action enhancing blood flow in the area of the sexual organ. As a result, cavernous bodies are maximally filled with blood and grow in size. Medicinal agents containing tadalafil allow restoring natural erection mechanism which is impossible without sexual stimulation.
It is well known that PDE5 inhibitors group includes not only tadalafil-containing medications. Sildenafil and vardenafil also struggle against erectile dysfunction. Recent research studies have demonstrated that medicines with active substance, tadalafil influence PDE6 – enzyme contained in eyes. In comparison with Levitra and Viagra the drugs with tadalafil do not practically affect PDE1 (enzyme located in brain and capable to cause hyperaemia and polycardia).
Interesting Facts about Apcalis SX
Before taking Apcalis SX and its analogies, you should find the reason of your functional disorders (andrologist or urologist will be very helpful here) in order to avoid two main delusions often ascribed to tadalafil-containing medicines:
- Apcalis SX is not aphrodisiacs (sexual stimulants) in a sense which is implied at the mundane level. This class of medicines doesn’t cause erection automatically, regardless of presence of sexual desire or its absence. Medicine’s action occurs with the possibility to provide enough blood supply to penis and only by means of sexual stimulation.
- Apcalis SX is not capable to solve problems of sexual issues if they are connected with some physiological disorders of penis. These medicines render effective assistance to men suffering from issues of mainly psychologic origin when a man gets into a vicious circle: failure-non-confidence-failure. Non-confidence causes problems of functional character. And this is tadalafil which is helpful to solve this problem.
If you know for sure the mode of operation of Apcalis SX and do not have any counter-indications, this drug is what you need.
Off-label Uses of Apcalis SX
Besides erectile dysfunction, Apcalis SX is indicative to patients suffering from benign prostatic hyperplasia and patients with ED having lower urinary tract symptoms on the top of benign prostatic hyperplasia.
Apcalis SX along with other agents
You need to contact your attending doctor of all medicines you take. Apcalis SX may be taken along with other medicines only in case it is recommended by a doctor or therapist.
You should read instructions of all medicines you take, including the one to Apcalis SX.
- It is strictly prohibited to take Apcalis SX along with nitrate-containing medications, nitrogen oxide donors, since the drug enhances hypotensive effect of them.
- The intake of cimetidine, itraconazole, ketoconazole, erythromycin enhance Apcalis’s effect.
- Apcalis SX is not taken along with antihyperglycemic agents
Apcalis SX combination with alcohol
The active component of this drug, tadalafil cannot be combined with alcohol. The intake of any alcoholic beverages is excluded from wine on out to strong ethanol. Moreover, alcohol may influence adversely man’s health condition causing a number of side-effects. It is worth mentioning that grapefruit juice is incompatible with active ingredients of Apcalis SX.
Apcalis SX altogether with food
Medical experts prove that tadalafil is not prohibited to be taken along with fat, spicy and salty food. Nevertheless, a slight diet is recommended in order not to aggravate the overall condition and accelerate the process of side-effects occurrence. It is better to exclude fried meat and fish, spicy seasoning, pastries, sweet baked goods and other fat dishes from ration.
Side-effects after Apcalis SX are quite rare.
After clinical trials there were fixed insignificant side-effects the quantity of which didn’t prevail 12% in tested group:
- Insignificant dermahemia
- Nose congestion
- Color sensation change
The most frequently met undesirable symptoms are headache and dyspepsia (11 and 7% cases accordingly). Side-effects connected with tadalafil intake were of either insignificant or moderate intensity, transient and reduced after continuation of medication intake.
Warnings, Precautions & Contraindications
Apcalis SX should be chewed and drunk with a lot of water or juice. But do not drink tadalafil with grapefruit juice. Some of substances contained in it are not compatible with tadalafil and may cause unpredictable consequences up to symptoms of overdose.
Recommended dose of Apcalis SX is 10mg. In case it doesn’t give desired effect, it should be increased up to 20mg. The interim between the intakes should be not less than 24 hours. Apcalis SX is sold without prescription.
Nevertheless, it is required to consult a therapist in order to exclude the possible counter-indications:
- Idiosyncrasy to tadalafil
- Erythroid myeloma
- Sickle-cell disease
- Renal system failure
- Deformation of penis of any origin
- Hepatic decompensation
Apcalis SX is not to be taken by women and persons under 18 years of age. Also, the drug cannot be taken along with nitrates-containing remedies, nitrogen oxides. Apcalis SX cannot be combined with ketoconazole, rifampicin, ritonavir, sacvinavir, erythromycin, itraconasole, and other drugs for erectile dysfunction. Besides, the medication should be taken with care by those patients who have endured heart attack or myocardial infarction or suffer from unstable arterial blood pressure.
The overdose may occur in case of exceed of maximally daily dose of 20mg or reduction of time between the intakes (less than 24 hours). If you have noticed symptoms of side-effects, seek immediate medical attendance in order to perform gastric lavage, clear blood of toxins and receive proper treatment.
Ways of Apcalis SX intake by various groups of patients
- Intake by middle-aged man – recommended dosage makes 20mg. It is taken 15 minutes before planned sexual intercourse regardless the food acceptance. Patients may have sex within 36 hours after the drug’s intake. Maximal frequency of intake is once a day.
- Intake by aged men – special dose titration is not required.
- Intake by men suffering from renal and hepatic failures – patients with renal (clearance of creatinin 30mL/min) and hepatic disorders do not need special dose titration.
- Intake by persons under 18 years – Apcalis SX is not to be taken by children and teenagers under 18 years of age.
Customer Questions About Apcalis SX
What are the main advantages of Apcalis SX over other tadalafil-containing drugs?
- Tadalafil in jelly form is absorbed faster than tablets. It is explained by the fact that jelly is in the dispersed form the absorption of which in system blood flow starts in mouth cavity. So, the effect of the intake is developed faster than of the standard pill.
- Due to absence of partial destruction by liver enzymes, Apcalis has a stronger effect in comparison with tablets.
- Jelly has a savory fruit flavor and is packed in hermetic bags which are easy to carry in a pocket. It may be diluted by water or any other non-alcoholic drink or taken in pure form by pressing out the bag contents in mouth.
- Jelly’s action is not only super-fast (10-15 minutes after the intake), but also long-lasting (36-48 hours). It has minimal and transient side-effects.
Can women take Generic Apcalis SX?
Apcalis SX is not designed to be taken by women.
How long does Apcalis SX effect last?
It is generally accepted that tadalafil in the form of jelly takes a faster action and gives less side-effects than traditional tableted form due to its quick absorption rate. Apcalis SX starts its effect in 10-15 minutes and lasts 36-48 hours. Besides, jelly is easier to swallow which is quite convenient for aged patients or persons with disturbed deglutitory function.
Can Apcalis SX be combined with alcohol?
Moreover, alcohol may influence adversely man’s health condition causing a number of side-effects.
Customer Reviews about Apcalis SX from My Canadian Pharmacy
I shouldn’t have thought that I had no powers in sex by the age of 40. I’ve heard many rumors about the pills and thought it was nonsense. But once I tried Apcalis SX jelly from Canadian Pharmacy and the result was devastating. I haven’t expected that. All night was top-class, even my wife told that I excelled myself. Now I use the jelly regularly before sex, but my wife doesn’t know this. Now I feel self-confidence like in my best of times.
Apcalis SX is convenient with its jelly form. The effect is terrific. I do not suffer from impotency, but I become more sensitive, have new feelings and no side effects at all. FYI – the jelly is very strong, so if you have things to do or somewhere to go – take the drug on weekend at home when you know for sure you needn’t go out.
Although I am young, I do have issues. Doctor has recommended tadalafil and I chose it in jelly form. I pleased my girl not once, the effect comes in 10 minutes lasting more than 24 hrs. Jelly form is awesome and sweet in comparison with tablets. After a month of use, everything fell into a groove))).